Table 82: Gingival Fibromatosis

Table 82a: Drugs associated with gingival fibrous hyperplasia.

• phenytoin
• amlodipine

• bepridil
• bleomycin
• cyclosporin
• diltiazem
• felodipine
• isradipine
• nicardipine
• nifedipine
• nimodipine
• nisoldipine
• nitrendipine
• oxidipine
• sodium valproate
• verapamil

Table 82b: Syndromes associated with gingival fibrous hyperplasia.

With Generalized Gingival Fibromatosis:

• Byars-Jurkiewicz syndrome (gingival fibromatosis, hypertrichosis, giant fibroadenomas of the breast, and kyphosis)
• Cross syndrome (gingival fibromatosis, microphthalmia, mental retardation, athetosis, and hypopigmentation
• Gingival fibromatosis and growth hormone deficiency
• Gingival fibromatosis, hypertrichosis, epilepsy, and mental retardation syndrome
• Jones-Hartsfield syndrome (gingival fibromatosis and sensorineural hearing loss)
• Laband syndrome (gingival fibromatosis; ear, nose, bone, and nail defects; and hepatosplenomegaly)
• Murray syndrome (gingival fibromatosis with juvenile hyaline fibromatosis)
• Ramon syndrome (gingival fibromatosis, hypertrichosis, cherubism, mental and somatic retardation, and epilepsy)
• Rutherford syndrome (gingival fibromatosis and corneal dystrophy)

With Papular Gingival Fibromatosis (Papulosis):

• Acanthosis nigricans
• Cowden syndrome (multiple hamartoma syndrome)
• Tuberous sclerosis