Bone marrow edema with focal osteosclerosis (49 y/o female).  Irregular brownish discoloration of the normally yellow/white marrow of the mandible is seen surrounding the inferior alveolar nerve, which has a brownish discoloration also and is somewhat delaminated.  The ramus and the angle are especially involved and the darkest areas showed focal necrosis microscopically.  Scattered white patches are ischemic osteosclerosis areas, some of which have been accentuated by precipitated salts during tissue processing (note the inferior border).